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The PCOS model is established using dehydroepiandrosterone ( DHEA ) by subcutaneous injection . ovarian apoptosis is assessed habituate terminal deoxynucleotidyl transferase dUTP nick-end pronounce ( TUNEL ) . real-time quantitative PCR ( RT-PCR ) and western spot are used to discover the expression of inflammatory ingredient and the even of angiogenesis-related agent in ovarian tissues . incendiary cells enumeration and ovarian angiogenesis are measure by immunofluorescence staining . This enquiry depict that TSP1 and ADSCs treatment can importantly reduce the incitive state of PCOS mice , ease the degree of ovarian cell apoptosis , optimise the ovarian histologic materialisation , and restitute the stage of related hormones . The proportionality of CD31-positive cubicle in PCOS mice returned to near-normal levels .

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